Principal Programmer- Biomarker

Site Name: USA - Pennsylvania - Philadelphia, UK - Hertfordshire - Stevenage Posted Date: Feb 12 2023 What do we do? GSK is one of the world's foremost pharmaceutical and healthcare companies, with statisticians and programmers working in Research and Development with a global footprint spanning the UK, US, EU, Canada and India. GSK’s speed and success in discovering and developing new medicines, therapies and vaccines is increasingly decided by scientific data and the effectiveness with which it can be captured, interrogated and understood. It’s our job in Statistical Programming to equip our scientific experts with data that is seamlessly curated, analysed and visualised. We support every stage of the path that each potential drug progresses along, from non-clinical research to commercial launch and lifecycle management. How do we do it? We are transforming and becoming a modern, innovative, agile function powered by multilingual coders, data engineers and data scientists who are all conversant in the latest approaches, capabilities and technologies. We’re proud of our adoption of R and our leadership of open-source coding collaborations across the Pharma industry. We are investing in a new statistical computing environment, a multimillion-pound modern data science and analytics platform that will allow us to surface and analyse every kind of clinical and non-clinical data using the latest in programming methodologies and languages (R, Python, SAS). Built-in automations will eliminate heavy manual and repetitive tasks and reduce cycle times from weeks to days. Additional initiatives include exploring machine learning to drive efficiencies for clinical reporting, developing desktop visualisation capabilities and we even have an annual challenge for Programmers who are rewarded for bringing new innovations into the department. What can we offer you? The data we deal with is increasingly complex and diverse, demanding a pioneering programming and analytics environment and a workforce who are continuously expanding their technical skills and looking for ways to innovate and experiment. Beyond the satisfaction of varied and interesting work in support of a really worthwhile mission, we will grow and develop you as an individual contributor and a potential leader in the field. And we don’t just invest in your technical competencies and capabilities. Communication, influencing and management skills as well as the ability to work in an agile and collaborative way are also important attributes of outstanding programmers and data specialists. Great results and high performers are rewarded, but also we’re a team with real camaraderie who care about each other and enjoy working together. Would you like a progressive career at the leading edge of transformation and innovation? Come and join our diverse global team of programmers and data scientists as we unlock the power of automation, analytics and visualisations to accelerate delivery of medicines and vaccines. Patients around the world are counting on us.” GSK is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to support our mission to improve the quality of human life by enabling people to do more, feel better and live longer. Oncology Biomarker Programming is committed to supporting the development of novel Oncology therapies via our exploratory Biomarker work. Current GSK Oncology portfolio consists of four key therapy areas: Immuno-Oncology, Oncology Cell & Gene Therapy, Synthetic Lethality, and Tumour Cell Targeting. US Hiring Locations: Collegeville, PA and Waltham, MA Canada Hiring Locations: Mississauga UK Hiring Locations: Stevenage, GSK House EU Hiring Locations: Netherlands, Belgium Remote Working: A variety of flexible working arrangements are available Key Responsibilities Creation of biomarker analysis datasets from a variety of file and formats from either internal or external labs/vendors. The candidate should be comfortable working with a diverse collection of data files in terms of the type (depending on the assays/platform used to generate the data), data format and size. Creation of graphs and tables related to biomarker data primarily for exploratory investigations (hypothesis generation or evaluation) with analysis requirements that may change throughout the life of the project. Automation of data creation, graphs, tables and certain Statistical analyses using R scripts and developing R-Shiny apps for delivering automated analysis solutions for end users. Act as a subject matter expert and work as a guide within own discipline to investigate new technology as directed. Provide technical contribution to complex tasks. Participate/Lead the planning and execution of multiple programming activities to deliver all required outputs Work as a lead within own discipline to investigate new technology as directed Ensure the collection of programs/outputs and issues are adequately managed for programming activities to achieve business outcomes. Apply learning from previous activities to result in quicker and more efficient completion of the current task. Ability to closely collaborate with major stakeholders in Translational Statistics, GSK’s Experimental Medicine Unit, Clinical Programming and Data Management. Share learnings with peers and contribute to internal technical discussions/forums. Closing Date for Applications: until filled Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.
LI-GSK Why you? Basic Qualifications We are looking for professionals with these required skills to achieve our goals: BSc in mathematics, statistics, data science, computer science or related discipline. Clinical Programming experience, with a thorough understanding of the end to end clinical trial process. Experience in R, SAS programming, and script/macro code development. Experience with other programming such as R-Shiny, Python, Power BI, JMP, SAS/GRAPH, SAS Output Delivery System. Preferred Qualifications If you have the following characteristics, it would be a plus: Working knowledge of relevant therapeutic area such as oncology Experience leading multiple studies Experience with writing and applying Metadata Specifications/Derivations Deliver presentations with clarity in internal forums and/or external professional industry meetings Able to explain technical approaches to peers and non-technical colleagues/settings Demonstrated effectiveness in both oral and written communications, able to express ideas and incorporate feedback to produce a completed quality deliverable Demonstrated ability to collaborate across functions. A solid level of understanding of the pharmaceutical regulatory and publishing processes (e.g. 21 CFR Part 11). Demonstrated knowledge of and experience in the application of CDISC data and standards Why GSK? Uniting science, technology and talent to get ahead of disease together GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more: Annual Report 2021 GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. 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