Scientist, Phenotypic Screening

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us Leads Discovery and Optimization (LDO) is a dynamic organization that supports the entire continuum of drug discovery from lead identification to clinical candidate delivery at Bristol Myers Squibb. LDO leverages state of the art technologies, complemented by deep subject matter expertise and broad scientific knowledge, to deliver innovative and comprehensive preclinical in vitro datasets to support our drug discovery pipeline in disease areas such as oncology, immunology, fibrosis, cardiovascular diseases, neuroscience and cell therapy. The Phenotypic Screening Center of Excellence (CoE) within LDO is seeking a highly motivated and innovative scientist to enable the phenotypic screening platform to support lead discovery and optimization in oncology, immunology, cardiovascular and fibrosis disease biology areas. Applicants must have a deep scientific understanding in one of the disease biology areas described above or related field and have hands-on experience developing complex cellular assays. Furthermore, the successful candidate will be required to develop phenotypic assays and to perform high-throughput phenotypic screening, hit assessment and lead optimization. The incumbent should possess strong collaborative and written/verbal communication skills and a positive attitude to interact with multiple stakeholders. This is a lab-based position. The incumbent should demonstrate personal leadership within the CoE, scientific leadership both at the bench and with data analysis and be adept at multi-tasking. Job Responsibilities Advance phenotypic screening technology with an emphasis on patho-physiologically relevant cellular models, including co-cultures, organoids, human derived iPSC, primary cells, micropatterned 2D culture, tissue-on-a-chip, or other 3D models. Design scalable assays with translationally relevant functional readouts, including phenotypic assays using high content screening (HCS), flow cytometry or other cutting-edge readout technologies, and apply the assays for high-throughput screening. In collaboration with other CoE members, develop hit deconvolution plans and execute hit triage assays to identify desirable compounds. Develop compelling scientific presentations and reports for internal review meetings and scientific journals. Act as point of contact with program teams, Data Analytics and Discovery IT colleagues. Basic Qualifications: Ba Bachelor’s Degree with 5+years of academic or industry experience Or Master’s Degree with 3+ years of academic or industry experience Or PhD and No years of experience Preferred Qualifications: PhD in in oncology, immunology, fibrosis or cardiovascular diseases or related field; 1-2 years of post doc experience would be a plus. Proven expertise with complex cellular assays is a must. Hands-on experience with experimentation using disease-relevant cellular models, such as co-cultures, primary cells, human derived iPSC, organoids, 3D or tissue-on-a-chip, is required. Knowledge/experience with phenotypic screening and hit de-convolution is preferred. Hands-on experience with HCS or flow cytometer and associated data analytics is desirable. A strong publication record in relevant disease biology or cell biology is desirable. A strong desire to succeed in cross-functional teams to establish productive collaborations. Demonstrated excellence in both written and oral communication. A “cutting edge” awareness of new technology advances and scientific knowledge in the phenotypic screening field is important. If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture. COVID-19 Information To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S. BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.