DMPK Project Specialist, Associate Director

Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham Posted Date: Feb 7 2023 Do you have experience in Biologics Drug Discovery and an interest in pharmacokinetics and translational PK/PD of antibody-based therapeutics? Are you interested in expanding your role? The GSK global DMPK organization is looking for a DMPK Project Specialist (Associate Director) to join the Discovery DMPK Project Specialist group, based in either Stevenage, UK or Philadelphia, USA. The candidate must have an in-depth knowledge of therapeutic antibody drug discovery (preferably including bispecifics and ADCs) and a keen interest in understanding the translational PKPD of antibody-based molecules. Working collaboratively with key matrix project team members (i.e. Project Leader, Biopharm Discovery, DMPK Modelling, Biology Lead etc.), across different therapeutic areas, you will be responsible for designing and delivering the DMPK strategy to ensure project progression through to FTIH. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Provide DMPK input into project strategy and DMPK data interpretation for Discovery stage therapeutic antibody projects up to Phase 1 clinical trials. Efficiently manage your time and project requests and be accountable for DMPK deliverables to ensure effective support of your projects. Ensure that translational PKPD approaches are at the heart of project strategy and used to design key biology and lead characterisation activities aligned with the needs of efficacious human dose prediction Implement best practices and share insight across the DMPK specialists group to help drive and embed strategic direction. Develop and maintain excellent working relations with key matrix partners in Discovery project teams, to ensure strategic alignment and optimal collaboration and communication. Responsible for coordinating and delivering high-quality DMPK contributions to governance documents for the projects you support. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: MS Degree with 7+ years in a field relevant to DMPK (e.g., Pharmacology, Biochemistry, Pharmacokinetics or Drug Metabolism) PhD with 3+ years in a field relevant to DMPK (e.g., Pharmacology, Biochemistry, Pharmacokinetics or Drug Metabolism) Preferred Qualifications: If you have the following characteristics, it would be a plus: PhD in a field relevant to DMPK (e.g., Pharmacology, Biochemistry, Pharmacokinetics or Drug Metabolism) with >5 years drug discovery experience Experience of DMPK Project Representation in Discovery with a variety of therapeutic antibody formats (e.g. mAbs, bispecifics, ADCs etc) Experience in developing Translational PKPD strategies and leveraging modeling approaches in Discovery projects for human dose predictions. Demonstrated ability to develop and maintain strong working relationships with peers and across matrix Project Teams. Excellent communication skills and high learning agility. Ability to manage project resources and budgets. An enthusiastic collaborator with a proven track record of building relationships and supporting high-performing teams from multiple disciplines. Experience, understanding and proven track record of working in therapeutic antibody drug discovery. Why GSK? GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
LI-GSK GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting For the Record site.