Senior Software Engineer - Sequence Learning

Site Name: London The Stanley Building Posted Date: Dec 6 2022 Senior Software Engineer - Sequence Learning At GSK we see a world in which advanced applications of artificial intelligence and machine learning (AI/ML) will allow us to develop novel therapies to existing diseases and to quickly respond to emerging or changing diseases with personalized drugs, driving better outcomes at reduced cost with fewer side effects. It is an ambitious vision that will require the development of products and solutions at the cutting edge of AI/ML. If that excites you, we'd love to chat. The AI/ML Sequence Learning Team applies machine learning and AI methods to biological sequence (DNA, RNA, protein) data from large-scale human genetic, functional genomic and single cell experiments. Models operating directly on sequence data that can infer how variants alter protein/RNA abundance, structure and function have the potential to be transformative in drug discovery, empowering us to find new life saving medicines. We are looking for a Senior Software Engineer with a track record of developing production grade AI-powered software solutions and an in-depth knowledge of modern software engineering best practices. This important role will be central in allowing us to scale our modelling efforts and build out an ecosystem of services that will support advanced sequence modelling efforts within the AI/ML team and across GSK. The candidate should be comfortable being fully accountable for the software engineering component of complex technical products. A background in genetics is not a requirement, but the ability to engage effectively with AI/ML and genetics subject matter experts will be an important part of the role. The AI/ML team is built on the principles of ownership, accountability, continuous development, and collaboration. We hire for the long term, and we're motivated to make this a great place to work. Our leaders will be committed to your career and development from day one. We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated. In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention. Find out more: Our approach to R&D In this role you will Lead the hands-on development of AI-powered services, taking responsibility for requirements engineering, software architecture design, implementation, testing, integration, maintenance and documentation Collaborate with AI/ML experts to develop modular, reusable, and scalable deep learning library components for training and inference pipelines Liaise with end users to ensure fit-for-purpose programming interfaces Work closely with AI/ML Platform Engineers to construct software solutions that are compatible with existing AI/ML infrastructure Mentor/coach AI/ML Engineers in software engineering best practices Deliver robust, tested and performant code in an agile development environment Exhibit excellent project management and communication skills, taking ownership and working transparently Closing Date for Applications: 20/12/22 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection +44 (0)808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process. *LI-GSK Why you? Qualifications & Skills: We are looking for professionals with these required skills to achieve our goals: A degree in a quantitative or engineering discipline (e.g. computer science, computational biology, bioinformatics, engineering, among others); OR equivalent work experience as a professional software engineer Several years’ experience of professional software development practices: code standards, code review, source control, CI/CD, testing, documentation, Agile, with the ability to mentor others in these practices Advanced Python programming skills and a track record of delivering robust software solutions Preferred Qualifications & Skills: If you have the following characteristics, it would be a plus: Familiarity with machine learning principles and state-of-the-art modelling approaches recent applied experience with major deep learning frameworks (PyTorch, TensorFlow) Contributions to open-source projects Background in genetics or molecular biology Experience working with biological sequence data (e.g. genomics, transcriptomics, proteomics) Experience with common bioinformatics tools (e.g. samtools) Why GSK? Uniting science, technology and talent to get ahead of disease together GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more: Annual Report 2021 GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce. As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only). We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. 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